What Do You See?

Special glasses let colorblind people see the world like never before

SHUTTERSTOCK

TYPICAL VIEW: Here's how fall foliage might appear to someone with normal color vision (left). 

COLORBLIND VIEW: And here's how the same scene might look with red-green colorblindness (right).

About 10 years ago, glass scientist Don McPherson was playing in an Ultimate Frisbee tournament in California. At the time, McPherson specialized in making glasses to protect surgeons’ eyes from lasers that they use to perform operations. Some of the doctors reported an unexpected effect of the safety glasses: The lenses seemed to make certain colors—like the deep red hue of blood—more vivid. A few surgeons even enjoyed wearing them outdoors as sunglasses. 

McPherson was wearing a pair at the Frisbee tournament when a teammate asked to borrow them. The friend put the glasses on and looked out at the field, scanning the end zone marked with bright orange cones. “Dude,” he exclaimed suddenly, “I can see the cones!” 

At first McPherson didn’t understand what his teammate was talking about. The friend, a talented player, explained that he was colorblind. He’d always had trouble distinguishing the orange cones from the green grass surrounding them—until he put on McPherson’s glasses and the colors popped like never before.

COLORBLINDNESS 101

Colorblindness can refer to a variety of color vision deficiencies ranging from difficulty in distinguishing certain colors to complete absence of color vision (which is very rare). Around 15 million Americans—more than 4 percent of the population—have some form of colorblindness. The most common is red-green colorblindness, which involves trouble telling apart colors containing red, yellow, or green. Most types of colorblindness don’t affect visual acuity, the sharpness of vision.

Colorblindness is usually inherited. It’s caused by problems with light-detecting cells in the eye called cones (see Inside the Human Eye). The eye normally has three types of cones, each containing a different light-sensitive molecule called a pigment. Each pigment is most sensitive to a different wavelength of light. Wavelength is the distance between the peaks of a wave of light energy. Wavelength is related to light’s color, but most light is a mix of wavelengths.

When light hits the back of the eye, the brain rapidly combines and interprets signals from the cones to create the perception of color. If any of the three cone pigments is missing or abnormal, a person will have some form of colorblindness.  

The genes for two of the pigments are located on the X chromosome, which plays a role in determining a person’s sex. Typically men have one X chromosome in each of their cells and women have two. 

If one of the cone pigment genes on a man’s X chromosome is abnormal, he’ll be colorblind: The abnormal gene is the only copy he has. A woman may have an abnormal gene on one X chromosome, but as long as she has a normal version of the gene on the other one, she’ll have full color vision. As a result, colorblindness is far more common in men than in women.

ALEXANDER KALUDOV/ALAMY

COLOR VISION TESTS: These circles made of dots are part of the Ishihara color-blindness test. Everyone should be able to see the number 12 (right). Colorblind people may be unable to see the number 6 (left).

SEEING DIFFERENTLY

Colorblind people do just fine most of the time but can run into problems in certain situations. Some may have trouble telling whether produce is ripe, seeing whether meat is properly cooked, and noticing skin rashes or sunburn. They also may be unable to distinguish the colors of traffic lights. In daylight they can often tell the lights apart by their positions on the traffic signal, but at night it may be impossible to see. 

In schools, “students sometimes have difficulties, since a lot of information on assignments may be color-coded,” says McPherson. The issue may even come up on tests. Teachers may not realize that certain students are colorblind—and students themselves may not know if they haven’t been tested. Currently, most states don’t require color vision testing in schools.

On the other hand, colorblindness may have some upsides. Research suggests that colorblind people can distinguish certain colors that look identical to viewers with standard color vision. And some types of colorblindness may give people an advantage at detecting camouflage. During World War II, colorblind servicemen reportedly spotted hidden enemy soldiers, ships, and weaponry that others couldn’t see.

HOW THE GLASSES WORK

ALEXANDER KALUDOV/ALAMY

WHAT NUMBER? Most viewers will see 29. Colorblind people may see 70 or no number.

After McPherson saw his Frisbee teammate’s reaction, he decided to focus on creating lenses for colorblind people. His glasses can compensate for certain types of red-green colorblindness by filtering out yellow light. Yellow falls between red and green on the electromagnetic spectrum, which includes all types of light arranged by wavelength.

Blocking some of that yellow light helps to more clearly separate the red and green light that hits the cones in the eye. That can help the wearer distinguish red from green when the signals from the cones are combined in the brain. “Color perception isn’t a simple reflex,” says Bevil Conway, a neuroscientist at Wellesley College in Massachusetts who studies visual perception. “It depends on heavy computation that the brain performs on the information it gets from the eye.”

RESTORING THE RAINBOW?

McPherson conducted experiments to find out how well the glasses worked. Some people with red-green colorblindness become much better at identifying colors with the glasses on, and some improve their performance on certain tests of color vision. 

The glasses don’t work for everyone. People who have an abnormal pigment may notice a big difference in their color vision, but people who are missing a pigment usually don’t see much improvement.

McPherson cofounded a company, EnChroma, that sells the glasses. Anyone can take a test at the company website to see how likely it is that the glasses will help (see Our Results). 

Some researchers hope to develop a permanent cure for colorblindness. In 2009, University of Washington scientist Jay Neitz injected a pigment gene into the eyes of two colorblind adult monkeys. Soon, the monkeys started passing tests of color vision that they had consistently failed before.

Someday, a gene-based fix could open people’s eyes to a colorful new world.

CORE QUESTION: What are some possible advantages and disadvantages of colorblindness? Cite evidence from the text.  

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