ONLINE EXCLUSIVE

Preparing for a “Twindemic”

Protect yourself from the flu and Covid-19 this winter

Bill Oxford / iStock / Getty Images

FLU SEASON: Medical experts are urging people to get their flu shots to prevent the spread of influenza and avoid a possible “twindemic.”

Last year, more than 35 million people in the U.S. came down with the flu. They suffered symptoms like fever, body aches, a cough, and a runny nose. About 30,000 of those individuals died from serious complications caused by the illness. Scientists worry that flu season, which peaks between December and February, could be even more deadly this year. That’s because it will coincide with the coronavirus pandemic, leading to what some call a “twindemic.”

“Influenza and Covid-19 could happen at the same time this year, in the fall and winter months,” says Dr. Sumon Chakrabarti, an infectious-diseases physician from Trillium Hospital in Toronto, Canada. “Right now, we are much more prepared for Covid-19 than we were in March. But if you have a bunch of cases happening at the same time, there is the chance that hospitals could get overwhelmed with patients.” That’s why it’s important for everyone to get a yearly flu vaccine, which helps prevent people from getting infected with the influenza virus. (To learn more, check out “Battling the Flu,” Science World, November 19, 2018)

DOUBLE DUTY?

With the threat of a twindemic, there’s another good reason to get your flu shot: People who receive it may be less likely to contract Covid-19. Recently, scientists at the Radboud University Medical Center in the Netherlands studied hospital employees who got the flu shot in 2019. The researchers found that these essential workers were 39 percent less likely to become infected with the coronavirus that causes Covid-19 than their unvacccinated colleagues.

The scientists acknowledge that individuals who got their flu shot might also be more likely to follow Covid-19 prevention guidelines, like social distancing and wearing a mask. But they believe this research supports the hypothesis that vaccines that target specific diseases, like the one for the flu, might also trigger the body’s disease-fighting immune system to fight off a range of other infections—including the coronavirus.

U.S. Center for Disease Control (both images)

DOUBLE TROUBLE: The viruses that cause Covid-19 (left) and the flu (right) are two different viruses that cause similar symptoms in infected people.

A WORD OF CAUTION

The results of this study don’t prove that the flu vaccine prevents Covid-19. This means that even if you’ve received a flu shot this year, you still need to take recommended steps to protect yourself from contracting Covid-19. For example, avoid gatherings, wear a mask outside your home, wash your hands, and practice social distancing. Many people are not following these guidelines, and as a result the U.S. leads the world in Covid-19 cases and deaths —topping 15 million cases and 284,000 deaths as of December 8.

Pharmaceutical companies around the world are currently working on vaccines designed specifically to fight the virus that causes Covid-19 (see “The Race for a Vaccine,” Science World online, October 28, 2020). This November, two pharmaceutical companies—Pfizer and Moderna—announced that their early vaccines were about 95 percent effective at preventing the disease among tens of thousands of trial volunteers.

Now, both of these vaccines may only be days away from receiving emergency authorization from the U.S. Food and Drug Administration (FDA), which would allow for the early distribution of the new vaccine to people in high-risk groups. However, these vaccines still require official approval from the FDA. As a result, the earliest they are likely to become widely available is sometime next year—probably after flu season.

Doctors recommend that everyone more than 6 months old get the vaccine against influenza. “Doing whatever you can to prevent influenza infection is really important this year,” says Dr. Nipunie Rajapakse (Ruj-uh-PUCK-shuh), a pediatric infectious diseases physician at the Mayo Clinic in Minnesota. And one of the best ways to do that, she says, is by getting a flu shot.

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